Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 7/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198035 | 0.95 | HRAS (0.51) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21207202 | 0.88 | HRAS (0.50) | HRASKRASCD274PDCD1LG2 | |
| SCHEMBL30222583 | 0.88 | HRAS (0.50) | HRASKRASCD274PDCD1LG2 | |
| SCHEMBL21207018 | 0.88 | HRAS (0.58) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL30222551 | 0.88 | HRAS (0.58) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21202173 | 0.87 | HRAS (0.48) | HRASKRASCD274PDCD1PIK3CA | |
| SCHEMBL21201481 | 0.82 | HRAS (0.57) | HRASKRASCD274PDCD1PDCD1LG2 | |
| SCHEMBL21207197 | 0.80 | HRAS (0.53) | HRASKRASCD274PDCD1LG2 | |
| SCHEMBL30222389 | 0.80 | HRAS (0.53) | HRASKRASCD274PDCD1LG2 | |
| SCHEMBL29066259 | 0.78 | HRAS (0.62) | HRASKRASCD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743421-A1 | COMPOUNDS | Oxford University Innovation Limited (GB) | 2020-12-02 | — | — | EP | claimed |
| WO-2019145718-A1 | COMPOUNDS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-08-01 | — | — | WO | claimed |