Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ME2 | P23368 | 5/20 | 0.48 |
| ▸ | ME1 | P48163 | 5/20 | 0.48 |
| ▸ | ME3 | Q16798 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924441 | 0.83 | AKR1C3 (0.65) | AKR1C3MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL188832 | 0.83 | AKR1C3 (0.65) | AKR1C3MAPTLMNANPSR1POLB | |
| SCHEMBL17320489 | 0.80 | AKR1C3 (0.61) | AKR1C3MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL188791 | 0.79 | AKR1C3 (0.60) | AKR1C3MAPTLMNANPSR1POLB | |
| SCHEMBL14923989 | 0.79 | AKR1C3 (0.64) | AKR1C3MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL21204502 | 0.79 | GFER (0.69) | MAPTLMNAALDH1A1MAPK1HPGD | |
| SCHEMBL22542023 | 0.78 | AKR1C3 (0.58) | AKR1C3MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL20883675 | 0.75 | AKR1C3 (0.56) | AKR1C3MAPTLMNAPOLBALDH1A1 | |
| SCHEMBL20274197 | 0.74 | AKR1C3 (0.62) | AKR1C3MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL20884954 | 0.74 | AKR1C3 (0.58) | AKR1C3MAPTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517536-A1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |