Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20883675 | 0.94 | AKR1C3 (0.56) | AKR1C3MAPTALDH1A1KMT2AHTT | |
| SCHEMBL12826300 | 0.88 | MAPT (0.54) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL25844190 | 0.86 | MAPT (0.65) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL25844191 | 0.84 | LMNA (0.57) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL764335 | 0.83 | MAPT (0.76) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL14924441 | 0.83 | AKR1C3 (0.65) | AKR1C3MAPTALDH1A1KMT2AHTT | |
| SCHEMBL11919049 | 0.83 | MAPT (0.53) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL17320597 | 0.82 | RORC (0.54) | MAPTALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL24451826 | 0.81 | AKR1C3 (0.62) | AKR1C3MAPTALDH1A1KMT2AHTT | |
| SCHEMBL28758087 | 0.80 | KDM4E (0.61) | MAPTALDH1A1KMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015187684-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-10 | — | — | WO | disclosed |