Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21204651 | 0.89 | DPP4 (0.37) | PIK3CDDPP4DPP8DPP9DPP7 | |
| SCHEMBL25094200 | 0.82 | PDE4B (0.35) | PIK3CDPDE4BALDH1A1NAMPT | |
| SCHEMBL12448268 | 0.82 | PDE4B (0.35) | PIK3CDPDE4BALDH1A1NAMPT | |
| SCHEMBL17660647 | 0.82 | PDE4B (0.35) | PIK3CDPDE4BALDH1A1NAMPT | |
| SCHEMBL20457873 | 0.80 | DPP4 (0.32) | PIK3CDDPP4PDE4B | |
| SCHEMBL22473034 | 0.79 | PIK3CD (0.41) | PIK3CDDPP4DPP8DPP9DPP7 | |
| SCHEMBL19888520 | 0.77 | PDE4B (0.37) | PIK3CDPDE4BNAMPT | |
| SCHEMBL12801554 | 0.75 | VNN1 (0.41) | PIK3CDMAPTPDE4BALDH1A1 | |
| SCHEMBL19322325 | 0.74 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL9221673 | 0.73 | SMN1; SMN2 (0.44) | PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517536-A1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |