Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197343 | 0.91 | SLC2A4 (0.53) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL21206102 | 0.87 | FFAR1 (0.47) | GRIA2FFAR1FFAR4S1PR1ENPP2 | |
| SCHEMBL19388034 | 0.82 | S1PR4 (0.50) | FFAR1FFAR4AOC3S1PR1FOLH1 | |
| SCHEMBL21206050 | 0.80 | FFAR1 (0.42) | FFAR1FFAR4HPGDSS1PR1FOLH1 | |
| SCHEMBL2450156 | 0.78 | AOC3 (0.56) | GRIA2AOC3 | |
| SCHEMBL12276187 | 0.78 | SLC2A4 (0.56) | DRD2DRD4ADRA1DADRA1AADRA1B | |
| SCHEMBL2224632 | 0.77 | MEN1 (0.64) | FFAR1FFAR4S1PR1FOLH1 | |
| SCHEMBL3206273 | 0.77 | S1PR5 (0.47) | S1PR1FOLH1 | |
| SCHEMBL5474619 | 0.77 | NAMPT (0.47) | FFAR1FOLH1 | |
| SCHEMBL3199896 | 0.77 | SPR (0.51) | FFAR1DRD2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922821-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2019-07-31 | — | — | EP | disclosed |