Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19034456 | 0.87 | TDP1 (0.45) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL24766871 | 0.86 | PRSS1 (0.47) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL22364111 | 0.85 | TDP1 (0.47) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL13907111 | 0.84 | PRSS1 (0.48) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL18881123 | 0.84 | TDP1 (0.49) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL22473613 | 0.83 | FAAH (0.42) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL11983712 | 0.83 | TDP1 (0.51) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL20123269 | 0.82 | TDP1 (0.50) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL21390226 | 0.82 | TDP1 (0.44) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL11974152 | 0.81 | PRSS1 (0.42) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190234956-A1 | METHOD FOR DETECTING CROSSLINKED PEPTIDES VIA REPRODUCIBLE FRAGMENTATION IN A MASS SPECTROMETER | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2019-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190234956-A1 | METHOD FOR DETECTING CROSSLINKED PEPTIDES VIA REPRODUCIBLE FRAGMENTATION IN A MASS SPECTROMETER | PTMS, DCLRE1A, PDAP1 | PRSS1 950/4885PRSS2 895/4885PRSS3 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.