SCHEMBL21213629

SCHEMBL21213629

c1ccc(-c2ccc3nc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c(-n4c5ccccc5c5cc6ccccc6cc54)nc3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PIK3R1 P27986 1/20 0.37
PIK3CA P42336 1/20 0.37
PTGER4 P35408 3/20 0.35
NPY5R Q15761 1/20 0.35
KDR P35968 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TSPO P30536 1/20 0.32
PTGES O14684 1/20 0.32
MAPK14 Q16539 1/20 0.32
RXFP1 Q9HBX9 2/20 0.31
ALDH1A1 P00352 3/20 0.31
KMT2A Q03164 2/20 0.31
TLR9 Q9NR96 1/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21212900 1.00 KDM4E (0.38) KDM4EATML3MBTL1PIK3R1PIK3CA
SCHEMBL21213630 0.96 KDM4E (0.38) KDM4EATML3MBTL1PIK3R1PIK3CA
SCHEMBL21212898 0.96 KDM4E (0.38) KDM4EATML3MBTL1PIK3R1PIK3CA
SCHEMBL22425576 0.94 L3MBTL1 (0.38) KDM4EATML3MBTL1PTGER4NPY5R
SCHEMBL22425634 0.92 KDM4E (0.41) KDM4EATML3MBTL1PIK3CAPTGER4
SCHEMBL21213312 0.92 L3MBTL1 (0.43) KDM4EATML3MBTL1PTGER4NPY5R
SCHEMBL21213485 0.91 PIK3R1 (0.41) KDM4EATML3MBTL1PIK3R1PIK3CA
SCHEMBL21213548 0.91 PIK3R1 (0.41) KDM4EATML3MBTL1PIK3R1PIK3CA
SCHEMBL22425526 0.90 KDM4E (0.39) KDM4EATML3MBTL1PIK3CAPTGER4
SCHEMBL21213714 0.90 KDM4E (0.39) KDM4EATML3MBTL1PTGER4NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581496-B2 Benzocarbazole-based compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20190237680-A1 BENZOCARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190237680-A1 BENZOCARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CYP1B1, CYP2C9, CYP3A4 KDM4E 879/4885ATM 4058/4885L3MBTL1 898/4885
US-11581496-B2 Benzocarbazole-based compound and organic light-emitting device comprising same CYP1B1, CYP2C9, CYP3A4 KDM4E 879/4885ATM 4058/4885L3MBTL1 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.