Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17730143 | 1.00 | IDO1 (0.63) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL17729249 | 0.85 | IDO1 (0.58) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL17730058 | 0.82 | IDO1 (0.53) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL23728528 | 0.81 | KDM4E (0.51) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL17747277 | 0.81 | IDO1 (0.78) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL22986537 | 0.81 | IDO1 (0.78) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL17729136 | 0.81 | IDO1 (0.78) | IDO1CYP2C9CYP3A4CYP2C8TDO2 | |
| SCHEMBL28164055 | 0.78 | IDO1 (0.52) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL28164107 | 0.78 | IDO1 (0.52) | IDO1KDM4EHTTDPP4DPP8 | |
| SCHEMBL28164616 | 0.78 | IDO1 (0.52) | IDO1KDM4EHTTDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092750-B | Pentafluoro sulfanyl substituted amide compound, preparation method and application thereof in medicine | 北京诺诚健华医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-07-19 | — | — | US | disclosed |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| EP-3747865-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3747865-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| CN-110092750-A | Amides compound that Pentafluorosulfanyl replaces, preparation method and its in application pharmaceutically | 北京诺诚健华医药科技有限公司 | 2019-08-06 | — | — | CN | disclosed |
| WO-2019144781-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 北京诺诚健华医药科技有限公司 | 2019-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | IDO1, IDO2, KYNU | IDO1 1/4885KDM4E 225/4885HTT 2814/4885 |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | IDO1, IDO2, KYNU | IDO1 1/4885KDM4E 225/4885HTT 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.