SCHEMBL21214736

SCHEMBL21214736

O=C(O)CC1C2CCC1C1C3CCC(C3)C21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.48
SLC6A12 P48065 5/20 0.37
SLC6A11 P48066 5/20 0.37
SLC6A13 Q9NSD5 5/20 0.37
SLC1A2 P43004 3/20 0.33
CYP1A2 P05177 2/20 0.33
SLC1A1 P43005 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC6A1 P30531 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRB2 P47870 2/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRR1 P24046 1/20 0.32
GABRA4 P48169 1/20 0.32
MEN1 O00255 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19090912 0.89 HSD11B1 (0.45) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL19090914 0.89 HSD11B1 (0.45) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL19090845 0.89 HSD11B1 (0.45) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL19091011 0.89 HSD11B1 (0.45) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL14123210 0.87 HSD11B1 (0.48) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL24631338 0.85 HSD11B1 (0.40) HSD11B1SLC6A12SLC6A11SLC6A13
SCHEMBL19982307 0.85 HSD11B1 (0.40) HSD11B1SLC6A12SLC6A11SLC6A13
SCHEMBL7859286 0.84 HSD11B1 (0.58) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL7046134 0.84 HSD11B1 (0.58) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2
SCHEMBL14123079 0.80 HSD11B1 (0.42) HSD11B1SLC6A12SLC6A11SLC6A13SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314945-A1 NEGATIVE-TONE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-05 US disclosed
US-11747726-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-05 US disclosed
US-20220397825-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, COMPOUND, AND ACID DIFFUSION CONTROLLING AGENT TOKYO OHKA KOGYO CO., LTD. (JP) 2022-12-15 US disclosed
US-20210055656-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, POLYMERIC COMPOUND, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2021-02-25 US disclosed
US-20200409262-A1 RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2020-12-31 US disclosed
US-20190235380-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIST FILM, PATTERN FORMING METHOD, CURED FILM, AND METHOD OF PRODUCING CURED FILM TOKYO OHKA KOGYO CO., LTD. (JP) 2019-08-01 US disclosed