Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866338 | 0.80 | PDE2A (0.52) | PDE2AALDH1A1STK17A | |
| SCHEMBL22866364 | 0.78 | PDE2A (0.56) | HDAC1HDAC6KMT2AHDAC3HDAC2 | |
| SCHEMBL5912903 | 0.75 | GCGR (0.43) | MEN1KMT2ASLC2A1P2RX7 | |
| SCHEMBL12515566 | 0.75 | MEN1 (0.47) | HPGDMEN1KMT2APDE2AALDH1A1 | |
| SCHEMBL13777948 | 0.75 | ESR1 (0.61) | HPGDNPSR1HDAC1HDAC6HDAC8 | |
| SCHEMBL13780250 | 0.75 | HDAC1 (0.41) | HPGDNPSR1HDAC1HDAC6HDAC8 | |
| SCHEMBL22261338 | 0.74 | JAK3 (0.63) | HPGDHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL7260597 | 0.74 | PDE5A (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18488333 | 0.73 | GPR84 (0.46) | HPGDKMT2AP2RX7ALDH1A1STK17A | |
| SCHEMBL3844908 | 0.73 | PRKCQ (0.42) | HPGDMEN1KMT2AHDAC3PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019147862-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2019-08-01 | — | — | WO | disclosed |