Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129 | 0.81 | ANPEP (0.55) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL12131751 | 0.80 | USP2 (0.55) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL20687626 | 0.79 | ALDH1A1 (0.50) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL146289 | 0.78 | — | — | |
| SCHEMBL23788919 | 0.77 | KMT2A (0.42) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL21214691 | 0.77 | KMT2A (0.42) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL25914484 | 0.77 | KMT2A (0.42) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL8749749 | 0.76 | — | — | |
| SCHEMBL20810611 | 0.76 | USP2 (0.46) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP | |
| SCHEMBL22548464 | 0.76 | USP2 (0.46) | KMT2ACYP2C19CYP2D6CYP2C9ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019147862-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2019-08-01 | — | — | WO | disclosed |