Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21216318 | 0.92 | KDM1A (0.42) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL24335834 | 0.81 | KDM1A (0.42) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL24335836 | 0.81 | KDM1A (0.42) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL21216118 | 0.79 | KDM1A (0.46) | ATMKDM1AHSD17B10MEN1KMT2A | |
| SCHEMBL18497645 | 0.78 | ATM (0.44) | ATMPDE8BALDH1A1HSD17B10MEN1 | |
| SCHEMBL18497643 | 0.78 | ATM (0.44) | ATMPDE8BALDH1A1HSD17B10MEN1 | |
| SCHEMBL190190 | 0.76 | PDE8B (0.47) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL2345014 | 0.75 | ATM (0.51) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL1551631 | 0.75 | ATM (0.51) | ATMKDM1APDE8BALDH1A1HSD17B10 | |
| SCHEMBL2354644 | 0.75 | ATM (0.51) | ATMKDM1APDE8BALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019145713-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2019-08-01 | — | — | WO | disclosed |