Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535084 | 0.86 | KDM1A (0.39) | GPR119PTPRBPTPN11 | |
| SCHEMBL20535903 | 0.75 | KDM1A (0.34) | — | |
| SCHEMBL21216112 | 0.74 | JAK2 (0.44) | JAK2JAK1PTPRBPTPN11KDM4E | |
| SCHEMBL21216231 | 0.74 | JAK2 (0.44) | JAK2JAK1PTPRBPTPN11KDM4E | |
| SCHEMBL20535067 | 0.74 | KDM4E (0.37) | AGTR2KDM4EHSD17B10 | |
| SCHEMBL21216118 | 0.73 | KDM1A (0.46) | JAK2JAK1PTPRBPTPN11KDM4E | |
| SCHEMBL29081317 | 0.71 | NR1H2 (0.38) | HSD17B10 | |
| SCHEMBL29081315 | 0.71 | NR1H2 (0.38) | HSD17B10 | |
| SCHEMBL20535916 | 0.70 | NR1D1 (0.35) | NR1D1KDM4EHSD17B10 | |
| SCHEMBL9918104 | 0.69 | NR1H2 (0.42) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019145713-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2019-08-01 | — | — | WO | disclosed |