SCHEMBL212172

SCHEMBL212172

O=S(=O)(ON=CC1CCCCCCCC1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.44
G6PC1 P35575 1/20 0.41
ALDH1A1 P00352 7/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ENPP3 O14638 3/20 0.39
ENPP1 P22413 3/20 0.39
ENPP2 Q13822 2/20 0.39
NPSR1 Q6W5P4 2/20 0.38
THRB P10828 1/20 0.38
MAPT P10636 2/20 0.37
HSP90AA1 P07900 1/20 0.37
XBP1 P17861 1/20 0.37
MPI P34949 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
PARL Q9H300 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212143 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL212624 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL214343 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL212142 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL212623 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL214342 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL212171 1.00 APLNR (0.44) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL213860 0.98 APLNR (0.42) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL213859 0.98 APLNR (0.42) APLNRG6PC1ALDH1A1KDM4EMEN1
SCHEMBL17257175 0.86 APLNR (0.35) APLNRG6PC1ALDH1A1ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed