SCHEMBL212177

SCHEMBL212177

CSOc1ccccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.58
ALDH1A1 P00352 8/20 0.58
HSD17B10 Q99714 6/20 0.58
HPGD P15428 6/20 0.58
HMGB1 P09429 2/20 0.58
NAPRT Q6XQN6 2/20 0.58
ESR1 P03372 1/20 0.58
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58
TSHR P16473 1/20 0.58
GGT1 P19440 1/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
BLM P54132 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HTT P42858 2/20 0.55
USP2 O75604 1/20 0.52
PDE3A Q14432 1/20 0.52
MAPT P10636 1/20 0.52
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28040604 0.98 KDM4E (0.56) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29402606 0.83 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL144897 0.83 KDM4E (0.57) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL3022599 0.82 KDM4E (0.55) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL14451226 0.81 KDM4E (0.55) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL3682302 0.81 KDM4E (0.59) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL11358522 0.81 KDM4E (0.56) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL11108804 0.80 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL27705464 0.80 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL29199294 0.79 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060012-A Preparation method of eplerenone and intermediate thereof 江西百思康瑞药业有限公司 2026-05-19 CN claimed
EP-3338813-B2 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2026-04-15 EP claimed
EP-3558399-B2 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2026-01-14 EP claimed
EP-4095097-B1 METAL-ADSORBING COMPOSITE MATERIAL BASED ON MAGNETIC GRAPHENE OXIDE AND METHOD FOR OBTAINING SAME UNIV MALAGA (ES) 2025-10-01 EP claimed
WO-2025059962-A1 ALS INHIBITOR SULFONYLUREA HERBICIDES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 成都新朝阳作物科学股份有限公司 2025-03-27 WO claimed
CN-119661444-A ALS inhibitor sulfonylurea herbicide and preparation method and application thereof 成都新朝阳作物科学股份有限公司 2025-03-21 CN claimed
CN-119191924-A Synthesis method of tetra-substituted-1, 3-diene dicarboxylic acid 兰州大学 2024-12-27 CN claimed
CN-119161341-A Green synthesis method of polycyclic dihydroquinazolinone derivative with antiviral activity 河北农业大学 2024-12-20 CN claimed
CN-119143756-A Green synthesis method of polycyclic quinazolinone derivative with antiviral activity 河北农业大学 2024-12-17 CN claimed
CN-117946028-B Synthesis method of 1, 4-benzothiazepine compound 南通大学 2024-09-24 CN claimed
US-6436996-B1 Modulation of nitric oxide production DUKE UNIVERSITY 2002-08-20 US claimed
EP-1187605-A1 NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS Thyreos Corporation (US) 2002-03-20 EP claimed
WO-2001070199-A1 MATRICES CONTAINING NITRIC OXIDE DONORS AND REDUCING AGENTS AND THEIR USE NOVOVASCULAR, INC. (US) 2001-09-27 WO claimed
EP-0784429-A4 METHOD AND FORMULATION OF STIMULATING NITRIC OXIDE SYNTHESIS KAESEMEYER W H (US) 2001-02-07 EP claimed
WO-2000078303-A1 NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS THYREOS CORPORATION (US) 2000-12-28 WO claimed
EP-1019079-A1 MODULATION OF NITRIC OXIDE PRODUCTION DUKE UNIVERSITY (US) 2000-07-19 EP claimed
WO-1999016464-A1 MODULATION OF NITRIC OXIDE PRODUCTION DUKE UNIVERSITY (US) 1999-04-08 WO claimed
EP-0784429-A1 METHOD AND FORMULATION OF STIMULATING NITRIC OXIDE SYNTHESIS Kaesemeyer, W., H. (US) 1997-07-23 EP claimed
US-5543430-A ADMINISTERING MIXTURE OF ARGININE AND VENOUS DILATOR UNTIL DESIRABLE STATE OF VASORELAXATION IS OBTAINED PALMETTO PHARMACEUTICALS, LLC 1996-08-06 US claimed
WO-1996010910-A9 METHOD AND FORMULATION OF STIMULATING NITRIC OXIDE SYNTHESIS 1996-05-23 WO claimed