Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402606 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL9257340 | 0.82 | SLC6A3 (0.54) | KDM4EALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL11358522 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL212177 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL27931686 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL144897 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| Ammonia Solution, Strong SCHEMBL28040604 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL3022599 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL1308799 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL11108804 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703750-B2 | Mixtures and methods for the induction of resistance in plants | ISAGRO S.P.A. (IT) | 2014-04-22 | — | — | US | disclosed |
| US-20100317519-A1 | Mixtures and methods for the induction of resistance in plants | ISAGRO S.P.A. (IT) | 2010-12-16 | — | — | US | disclosed |
| US-20070173459-A1 | Mixtures and methods for the induction of resistance in plants | ISAGRO S.P.A. (IT) | 2007-07-26 | — | — | US | disclosed |
| US-6211212-B1 | DRUGS WITH AMIDE AND ESTER GROUPS AS ENZYME INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0970062-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998040056-A2 | PYRROLIDINE AND THIAZOLE DERIVATIVES WITH METALLO-BETA-LACTAMASE INHIBITORY PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1998-09-17 | — | — | WO | disclosed |
| US-4221800-A | ANTIALLERGENS, ANTIHISTAMINES | MILES LABORATORIES, INC. (US) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173459-A1 | Mixtures and methods for the induction of resistance in plants | SLC11A2, MYD88, ME2 | KDM4E 4408/4885ALDH1A1 2944/4885HSD17B10 2526/4885 |
| US-20100317519-A1 | Mixtures and methods for the induction of resistance in plants | SLC11A2, MYD88, ME2 | KDM4E 4408/4885ALDH1A1 2944/4885HSD17B10 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.