Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8615986 | 0.98 | CYP2D6 (0.61) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Bromide SCHEMBL29757574 | 0.80 | KCNH2 (0.53) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Ambenonium SCHEMBL284678 | 0.79 | CHRM2 (1.00) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Ambenonium SCHEMBL133487 | 0.78 | CHRM2 (0.97) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| SCHEMBL31658954 | 0.77 | IDO1 (0.50) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Ambenonium SCHEMBL5060921 | 0.77 | CHRM2 (0.94) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL14675356 | 0.76 | BCHE (0.60) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL22264987 | 0.76 | BCHE (0.51) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL20520489 | 0.74 | TAAR1 (0.43) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 | |
| SCHEMBL20590194 | 0.74 | CHRM2 (0.39) | CYP2D6SLC6A2SLC6A4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8090298-B2 | Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100104316-A1 | ELECTROSTATIC CHARGING MEMBER, ELECTROSTATIC CHARGING DEVICE, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2180376-A2 | Electrostatic charging member, electrostatic charging device, process cartridge and image forming apparatus | Fuji Xerox Co., Ltd. (JP) | 2010-04-28 | — | — | EP | disclosed |