Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18132145 | 0.95 | OTUD7B (0.40) | OTUD7BCRBNDDB1GRIN1GRIN2A | |
| SCHEMBL17611720 | 0.92 | OTUD7B (0.46) | OTUD7BCRBNDDB1GRIN1GRIN2A | |
| SCHEMBL21224568 | 0.84 | OTUD7B (0.37) | OTUD7BCRBNDDB1GRIN1GRIN2A | |
| SCHEMBL31580822 | 0.83 | OTUD7B (0.36) | OTUD7BCRBNDDB1GRIN1GRIN2A | |
| SCHEMBL20395821 | 0.82 | OTUD7B (0.53) | OTUD7BCRBNDDB1 | |
| SCHEMBL18113471 | 0.82 | OTUD7B (0.53) | OTUD7BCRBNDDB1 | |
| SCHEMBL20395783 | 0.82 | OTUD7B (0.53) | OTUD7BCRBNDDB1 | |
| SCHEMBL22975109 | 0.79 | USP30 (0.40) | CRBNDDB1GRIN2BACACB | |
| SCHEMBL2728185 | 0.79 | OTUD7B (0.38) | OTUD7BCRBNDDB1GRIN1GRIN2A | |
| SCHEMBL19852842 | 0.78 | OTUD7B (0.45) | OTUD7BCYP1A2CYP3A4ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
| EP-3746442-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | Aptinyx Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| WO-2019152678-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2019-08-08 | — | — | WO | disclosed |