Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212459 | 0.75 | MC4R (0.35) | NPC1RAB9AGRM5MC4RMAPT | |
| SCHEMBL17257082 | 0.74 | NPC1 (0.41) | NPC1RAB9AHSD11B1 | |
| SCHEMBL17257078 | 0.74 | NPC1 (0.41) | NPC1RAB9AHSD11B1 | |
| SCHEMBL2045918 | 0.71 | NPC1 (0.59) | NPC1RAB9ATSHRALDH1A1HSD11B1 | |
| SCHEMBL2045062 | 0.71 | NPC1 (0.59) | NPC1RAB9ATSHRALDH1A1MAPT | |
| SCHEMBL19100010 | 0.69 | NPC1 (0.42) | NPC1RAB9ATSHRHRH3TP53 | |
| SCHEMBL2044477 | 0.69 | TSHR (0.48) | NPC1RAB9ATSHRALDH1A1MAPT | |
| SCHEMBL2050061 | 0.68 | RAB9A (0.47) | NPC1RAB9ATSHRHRH3ALDH1A1 | |
| SCHEMBL7373187 | 0.68 | RAB9A (0.56) | NPC1RAB9ATSHRALDH1A1MAPT | |
| SCHEMBL2050063 | 0.68 | RAB9A (0.47) | NPC1RAB9ATSHRHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8541509-B2 | Polymers functionalized with protected oxime compounds | BRIDGESTONE CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-1913036-B1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-7820765-B2 | Amine functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20100120976-A1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |
| EP-1913036-A1 | AMINE FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015872-A1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2007-02-08 | — | — | WO | disclosed |