SCHEMBL212291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2733655	0.87	HDAC1 (0.48)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL212261	0.86	MAP2K1 (0.42)	MEN1KMT2AMAP2K1ALDH1A1
	SCHEMBL209935	0.84	HDAC1 (0.53)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL212292	0.84	MAP2K1 (0.40)	MEN1KMT2AMAP2K1ALDH1A1GAA
	SCHEMBL10272799	0.83	KDM4E (0.41)	RAB9AMEN1KMT2AMAP2K1ALDH1A1
	SCHEMBL1063066	0.81	HPGD (0.51)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL1079349	0.81	HDAC1 (0.47)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL1065300	0.78	HDAC1 (0.49)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL14425112	0.77	KDM4E (0.50)	RAB9AMEN1KMT2AMAP2K1ALDH1A1
	SCHEMBL13390030	0.73	ALDH1A1 (0.53)	RAB9AMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.