Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167264 | 1.00 | CHRNB2 (0.63) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| SCHEMBL170704 | 1.00 | CHRNB2 (0.63) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL27952288 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL3517185 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL12497423 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL841177 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL2522634 | 0.96 | CHRNB2 (0.65) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28855199 | 0.94 | CYP2D6 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Methyl Alcohol SCHEMBL27512085 | 0.94 | CHRNB2 (0.58) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28855198 | 0.94 | CYP2D6 (0.61) | CHRNB2CHRNA7CHRNA4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120117949-A | Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine | 湖南大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119606059-A | Preparation method of filter element material for enhancing tobacco smoke adsorption | 奥伯风环境科技(南京)有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-115108957-B | Synthesis method of chiral 2-phenylpyrrolidine | 深圳博瑞医药科技有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-115108957-A | Synthesis method of chiral 2-phenylpyrrolidine | 深圳博瑞医药科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| EP-3773725-A1 | TREATMENT OF TRK-ASSOCIATED CANCERS | Loxo Oncology Inc. (US) | 2021-02-17 | — | — | EP | claimed |
| US-20210023086-A1 | TREATMENT OF TRK-ASSOCIATED CANCERS | LOXO ONCOLOGY, INC. | 2021-01-28 | — | — | US | claimed |
| EP-3700576-A1 | FORMULATIONS OF A MACROCYCLIC TRK KINASE INHIBITOR | Array Biopharma Inc. (US) | 2020-09-02 | — | — | EP | claimed |
| WO-2019191659-A1 | TREATMENT OF TRK-ASSOCIATED CANCERS | LOXO ONCOLOGY, INC. (US) | 2019-10-03 | — | — | WO | claimed |
| CN-104592163-B | A kind of synthetic method of chirality 2-Phenylpyrrolidine | 爱斯特（成都）生物制药有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-104592163-A | Synthetic method of chiral 2-phenylpyrrolidine | ASTATECH CHENGDU BIOPHARM CO LTD | 2015-05-06 | — | — | CN | claimed |
| EP-0188805-B1 | 1,3-DITHIOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| EP-0188805-A1 | 1,3-Dithiole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | claimed |
| EP-4747245-A1 | PHARMACEUTICAL COMPOUNDS | Almac Discovery Limited (GB) | 2026-05-27 | — | — | EP | disclosed |
| CN-122059926-A | Heterocyclic degradation determinants for target protein degradation | C4医药公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2026102082-A1 | ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-0130069-A2 | Hexahydropyrrolo (2,1-a) isoquinoline derivatives | McNeilab, Inc. (US) | 1985-01-02 | — | — | EP | disclosed |
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |
| US-4191576-A | SULFONYL-SUBSTITUTED PYRROLIDINE, OXAZOLIDINE OR THIAZOLIDINE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-03-04 | — | — | US | disclosed |
| US-4163671-A | PYRROLIDINE OR THIAZOLIDINE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210023086-A1 | TREATMENT OF TRK-ASSOCIATED CANCERS | TP53, NCOA3, NCOA1 | CHRNB2 2266/4885CHRNA7 3301/4885CHRNA4 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.