Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 6/20 | 0.36 |
| ▸ | NPY1R | P25929 | 4/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385917 | 0.89 | DPP7 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL23394645 | 0.89 | DPP7 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL21323139 | 0.89 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL19450715 | 0.89 | DPP7 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL22848364 | 0.88 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL28234596 | 0.88 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL22797764 | 0.88 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL20795868 | 0.88 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL21137521 | 0.87 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6047671 | 0.87 | C3AR1 (0.46) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521314-B1 | ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN THERAPY | MC SAF (FR) | 2021-02-24 | — | — | EP | disclosed |
| EP-3521314-A1 | NEW ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN TREATMENT | Université François Rabelais (FR) | 2019-08-07 | — | — | EP | disclosed |