SCHEMBL6047671

SCHEMBL6047671

CC(C)[C@@H](N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
C3AR1 Q16581 1/20 0.46
NOD1 Q9Y239 3/20 0.43
DPP4 P27487 2/20 0.41
DPP8 Q6V1X1 2/20 0.41
DPP9 Q86TI2 2/20 0.41
DPP7 Q9UHL4 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.40
FOLH1 Q04609 2/20 0.40
FAP Q12884 1/20 0.39
GNPAT O15228 1/20 0.39
SHMT1 P34896 1/20 0.39
ECE1 P42892 2/20 0.38
MEN1 O00255 1/20 0.38
KLK7 P49862 1/20 0.38
KMT2A Q03164 1/20 0.38
FNTA P49354 3/20 0.38
FNTB P49356 3/20 0.38
PGGT1B P53609 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16801786 1.00 C3AR1 (0.46) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL28819908 1.00 C3AR1 (0.46) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL16862613 1.00 C3AR1 (0.46) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL16862522 1.00 C3AR1 (0.46) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL29359380 1.00 C3AR1 (0.46) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL27736911 0.92 FOLH1 (0.46) C3AR1NOD1FOLH1
Trifluoroacetic Acid SCHEMBL30532197 0.92 C3AR1 (0.41) C3AR1NOD1DPP4DPP8DPP9
SCHEMBL2107432 0.92 FOLH1 (0.46) C3AR1NOD1FOLH1
SCHEMBL1711082 0.92 FOLH1 (0.46) C3AR1NOD1FOLH1
SCHEMBL30942556 0.92 DPP7 (0.48) C3AR1NOD1DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF IMMUNOGEN, INC. 2025-01-09 US claimed
CN-113769108-B Conjugates of cysteine engineered antibodies 伊缪诺金公司 2024-11-08 CN claimed
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA IMMUNOGEN, INC. (US) 2024-07-11 US claimed
EP-4374850-A2 METHODS OF PREVENTING METHIONINE OXIDATION IN IMMUNOCONJUGATES ImmunoGen, Inc. (US) 2024-05-29 EP claimed
US-20240165256-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER IMMUNOGEN INC (US) 2024-05-23 US claimed
EP-4347661-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA ImmunoGen, Inc. (US) 2024-04-10 EP claimed
CN-117730098-A Treatment of cancer in patients with soluble FR-alpha 伊缪诺金公司 2024-03-19 CN claimed
CN-117729942-A Methods for increasing efficacy of ADAM 9-targeted immunoconjugates in the treatment of cancer 伊缪诺金公司 2024-03-19 CN claimed
CN-106604927-B Cytotoxic benzodiazepine derivatives 伊缪诺金公司 2022-08-09 CN claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 US claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed
US-20060052288-A1 Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor MITSUBISHI TANABE PHARMA CORPORATION (JP) 2006-03-09 US claimed
EP-1418947-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSACCHARIDE CONJUGATES FOR INHIBITING THE METASTASIS OR PREVENTING THE RECURRENCE OF MALIGNANT TUMOR TANABE SEIYAKU CO., LTD. (JP) 2004-05-19 EP claimed
US-20030092608-A1 Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor TANABE SEIYAKU CO., LTD. (JP) 2003-05-15 US claimed
WO-2003015826-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYSACCHARIDE CONJUGATES FOR INHIBITING THE METASTSIS OR PREVENTING THE RECURRENCE OF MALIGANT TUMOR TANABE SEIYAKU CO., LTD. (JP) 2003-02-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092608-A1 Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor CD44, MUC1, HGFAC C3AR1 873/4885NOD1 2576/4885DPP4 607/4885
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF C3AR1 104/4885NOD1 3543/4885DPP4 1262/4885
US-20240165256-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER ADAM9, TMPRSS15, ADAM17 C3AR1 1848/4885NOD1 4742/4885DPP4 466/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF C3AR1 104/4885NOD1 3543/4885DPP4 1262/4885
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA FOLR1, FOLR2, FRS2 C3AR1 1401/4885NOD1 4832/4885DPP4 4488/4885
US-20060052288-A1 Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor CD44, MUC1, HGFAC C3AR1 873/4885NOD1 2576/4885DPP4 607/4885
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF GABRA6, GABRA2, GABRA1 C3AR1 210/4885NOD1 2079/4885DPP4 4358/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG C3AR1 609/4885NOD1 3411/4885DPP4 2235/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA C3AR1 333/4885NOD1 734/4885DPP4 2000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.