Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20739105 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL7607468 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL12944390 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL20158427 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL15692085 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL84332 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL22315797 | 0.93 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| SCHEMBL21566843 | 0.92 | SIRT1 (0.41) | SPHK1 | |
| Hydrochloric Acid SCHEMBL28466185 | 0.92 | NPY4R (0.38) | HTTSPHK1SPHK2 | |
| Hydrochloric Acid SCHEMBL28466191 | 0.92 | NPY4R (0.38) | HTTSPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521314-A1 | NEW ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN TREATMENT | Université François Rabelais (FR) | 2019-08-07 | — | — | EP | disclosed |