Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516099 | 0.93 | CASP2 (0.42) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL25516101 | 0.93 | CASP2 (0.42) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL15082721 | 0.92 | SMN1; SMN2 (0.54) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL15888700 | 0.92 | SMN1; SMN2 (0.54) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL2124347 | 0.91 | CASP2 (0.44) | TSHRCASP2NAAAALDH1A1FAAH | |
| SCHEMBL21121019 | 0.89 | CASP2 (0.58) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL12508016 | 0.88 | CASP2 (0.61) | TSHRCASP2NAAAFAAHEPHX2 | |
| SCHEMBL24341463 | 0.87 | CASP2 (0.55) | TSHRCASP2RECQLNAAAFAAH | |
| SCHEMBL21538797 | 0.87 | CASP2 (0.60) | TSHRCASP2RECQLSMN1; SMN2NAAA | |
| SCHEMBL2122730 | 0.87 | CASP2 (0.50) | TSHRCASP2RECQLNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998289-B1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORP (JP) | 2019-08-07 | — | — | EP | disclosed |