Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15937141 | 0.81 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL21233890 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL18806207 | 0.67 | — | — | |
| SCHEMBL21233888 | 0.66 | — | — | |
| SCHEMBL21234100 | 0.64 | GRIN2B (0.38) | — | |
| SCHEMBL21233891 | 0.62 | HSD11B1 (0.36) | PIK3CD | |
| SCHEMBL25758680 | 0.62 | — | — | |
| SCHEMBL21233955 | 0.60 | — | — | |
| SCHEMBL21234117 | 0.60 | — | — | |
| SCHEMBL15936985 | 0.58 | KMT2A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152696-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2019-08-08 | — | — | WO | disclosed |