SCHEMBL2123445

SCHEMBL2123445

NC1(C(=O)c2ccccc2O)N=CN=N1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.44
KDM4E B2RXH2 6/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.41
CA1 P00915 2/20 0.41
CA9 Q16790 2/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
HMGB1 P09429 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA7 P43166 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CA14 Q9ULX7 1/20 0.41
GAA P10253 2/20 0.38
HIF1A Q16665 2/20 0.38
MPO P05164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11769770 0.77 MAPT (0.39) HPGDKDM4EALDH1A1MAPTHSD17B10
Salicylamide SCHEMBL27497234 0.63 KDM4E (1.00) HPGDKDM4EALDH1A1MAPTHSD17B10
Salicylamide SCHEMBL29384763 0.63 KDM4E (1.00) HPGDKDM4EALDH1A1MAPTHSD17B10
Salicylamide SCHEMBL21646 0.63 KDM4E (1.00) HPGDKDM4EALDH1A1MAPTHSD17B10
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.62 HPGD (0.67) HPGDKDM4EALDH1A1MAPTHSD17B10
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.62 HPGD (0.67) HPGDKDM4EALDH1A1MAPTHSD17B10
SCHEMBL29861559 0.62 KDM4E (0.67) HPGDKDM4EALDH1A1MAPTHSD17B10
SCHEMBL9797513 0.62 KDM4E (0.67) HPGDKDM4EALDH1A1MAPTHSD17B10
Salicylamide SCHEMBL723112 0.61 KDM4E (0.95) HPGDKDM4EALDH1A1MAPTHSD17B10
Salicylamide SCHEMBL18729462 0.61 KDM4E (0.95) HPGDKDM4EALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693698-B Multi-functional hindered amine light stabilizer 巴斯夫欧洲公司 2019-11-22 CN disclosed
CN-110446749-A Light stabilizer mixture BASF SE 2019-11-12 CN disclosed
CN-104755470-B Stabilizer compositions containing substituted chroman compounds and methods of use thereof 塞特克技术公司 2019-11-08 CN disclosed
CN-105683313-B Purposes of 2- (2- hydroxyphenyl) benzotriazole cpd in coating as UV absorbent 巴斯夫欧洲公司 2019-09-17 CN disclosed
CN-106715560-B Organic oxygroup acid imide is used as the purposes of radical-forming agent in the plastic, generates the method for free radical and the purposes of this method 弗劳恩霍弗应用研究促进协会 2019-08-27 CN disclosed
CN-107250238-B Light stabilization of polyolefins film, band and monofilament 巴斯夫欧洲公司 2019-08-20 CN disclosed
CN-106536613-B High-efficiency stabilizer 巴斯夫欧洲公司 2019-06-28 CN disclosed
CN-109642049-A Additive agent mixture 巴斯夫欧洲公司 2019-04-16 CN disclosed
CN-105960432-B Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers 巴斯夫欧洲公司 2019-02-15 CN disclosed
CN-105694097-B A kind of additive 广州铂钡信息科技有限公司 2017-03-01 CN disclosed
CN-1204666-A Low gloss thermoplastic resin composition GEN ELECTRIC (US) 1999-01-13 CN disclosed
CN-1133859-A Stabilizer combination CIBA GEIGY AG (CH) 1996-10-23 CN disclosed
EP-0374751-A2 Water-soluble light-projecting materials CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
EP-0365469-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
EP-0354184-A2 Compounds containing substituted piperidine groups for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed
EP-0345220-A2 Polyamines partially substituted by bis-piperidyl-triazines CIBA-GEIGY AG (CH) 1989-12-06 EP disclosed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed
EP-0317508-A2 Aminic orthoester stabilized compositions CIBA-GEIGY AG (CH) 1989-05-24 EP disclosed
EP-0314623-A2 Substituted hydroxylamine ester stabilizers CIBA-GEIGY AG (CH) 1989-05-03 EP disclosed
EP-0313517-A2 Aliphatic esters of 1,3,2-oxazaphospholidines CIBA-GEIGY AG (CH) 1989-04-26 EP disclosed