Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.39 |
| ▸ | FURIN | P09958 | 4/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12672688 | 1.00 | FAP (0.45) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL13893442 | 1.00 | FAP (0.45) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL24823239 | 0.94 | FAP (0.47) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL27406908 | 0.94 | FAP (0.46) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL24622056 | 0.93 | FAP (0.49) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL24622057 | 0.93 | FAP (0.49) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL28365735 | 0.91 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL17178689 | 0.91 | FAP (0.44) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL3798438 | 0.91 | FAP (0.44) | FAPMAP1LC3BFURINSIRT2SIRT1 | |
| SCHEMBL18391329 | 0.91 | FAP (0.44) | FAPMAP1LC3BFURINSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521292-A1 | BIFUNCTIONAL CYTOTOXIC AGENTS | Pfizer Inc (US) | 2019-08-07 | — | — | EP | disclosed |