Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 8/20 | 0.39 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225625 | 1.00 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL21225386 | 1.00 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL25532234 | 0.91 | PYGL (0.38) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL25531407 | 0.90 | PYGL (0.38) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL25531409 | 0.90 | PYGL (0.38) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL25532231 | 0.90 | PYGL (0.38) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL21225298 | 0.86 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL21225563 | 0.86 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL21225314 | 0.86 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 | |
| SCHEMBL21225322 | 0.86 | PYGL (0.39) | PYGLPYGMHRH4EHMT2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152883-A1 | INHIBITORS OF PROTEIN ARGININE DEIMINASES | PADFORWARD LLC (US) | 2019-08-08 | — | — | WO | disclosed |