Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 5/20 | 0.37 |
| ▸ | CDK8 | P49336 | 5/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18756194 | 0.82 | CHRM1 (0.46) | CHRM1CCNCCDK8PTGDR2AXL | |
| SCHEMBL18725462 | 0.81 | CHRM1 (0.67) | CHRM1AXLMERTK | |
| SCHEMBL18756195 | 0.80 | CCNC (0.45) | CHRM1CCNCCDK8PTGDR2TTK | |
| SCHEMBL18725468 | 0.73 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL18725465 | 0.73 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL18725466 | 0.73 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL18756535 | 0.70 | CYP11B1 (0.50) | CHRM1TTKGRM2 | |
| SCHEMBL21235161 | 0.69 | KCNH2 (0.41) | CHRM1GRM2 | |
| SCHEMBL20477698 | 0.69 | KCNH2 (0.50) | CHRM1CCNCCDK8PTGDR2AXL | |
| SCHEMBL20477702 | 0.69 | KCNH2 (0.50) | CHRM1CCNCCDK8PTGDR2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156397-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |