Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236931 | 0.86 | SCN9A (0.62) | SCN9AKDM4E | |
| SCHEMBL21236837 | 0.81 | SCN9A (0.72) | SCN9A | |
| SCHEMBL21236892 | 0.78 | SCN9A (0.67) | SCN9A | |
| SCHEMBL21236981 | 0.78 | SCN9A (0.67) | SCN9A | |
| SCHEMBL21236943 | 0.78 | SCN9A (0.67) | SCN9AKDM4E | |
| SCHEMBL21236866 | 0.75 | SCN9A (0.69) | SCN9A | |
| SCHEMBL21236886 | 0.74 | SCN9A (0.70) | SCN9A | |
| SCHEMBL21236860 | 0.74 | SCN9A (0.70) | SCN9A | |
| SCHEMBL11160098 | 0.71 | SCN9A (0.44) | SCN9AKDM4EMEN1KMT2A | |
| SCHEMBL16129942 | 0.70 | ALDH1A1 (0.62) | SCN9ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616441-B1 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2019-08-07 | — | — | EP | disclosed |