Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22696978 | 0.90 | GABRA1 (0.41) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL22696915 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL24966049 | 0.69 | GABRA1 (0.36) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL22696979 | 0.69 | GABRA1 (0.41) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL22696652 | 0.69 | GABRA1 (0.72) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL22756022 | 0.69 | GABRA1 (0.72) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL24966010 | 0.68 | BRD4 (0.43) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL24966089 | 0.68 | GABRA1 (0.43) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL22696698 | 0.68 | GABRA1 (0.43) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 | |
| SCHEMBL24967324 | 0.65 | GABRA1 (0.38) | GABRA1GABRB2CYP1A2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149228-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | 成都安诺晨创医药科技有限公司 | 2019-08-08 | — | — | WO | disclosed |