Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456039 | 0.78 | MAPT (0.55) | GAA | |
| SCHEMBL21238828 | 0.75 | PDE10A (0.50) | PDE10A | |
| SCHEMBL17456001 | 0.68 | PIK3CD (0.46) | PDE10A | |
| SCHEMBL17464261 | 0.68 | CYP11B1 (0.42) | PDE10A | |
| SCHEMBL17455962 | 0.67 | PDE10A (0.45) | PDE10A | |
| SCHEMBL17456004 | 0.65 | SMN1; SMN2 (0.52) | GAA | |
| SCHEMBL17456051 | 0.65 | PIK3CD (0.54) | — | |
| SCHEMBL17455969 | 0.65 | HTR2B (0.43) | PDE10AGAA | |
| SCHEMBL17456017 | 0.64 | NAMPT (0.53) | GAAL3MBTL1 | |
| SCHEMBL17456029 | 0.63 | PDE10A (0.47) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982666-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |