Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239548 | 0.95 | KCNH2 (0.50) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21239605 | 0.93 | KCNH2 (0.53) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21239567 | 0.93 | KCNH2 (0.53) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21113641 | 0.84 | KCNH2 (0.37) | KCNH2ALDH1A1CNR2NPSR1 | |
| SCHEMBL21113669 | 0.83 | KCNH2 (0.33) | KCNH2ALDH1A1MAPTNPSR1 | |
| SCHEMBL21113681 | 0.80 | KCNH2 (0.40) | KCNH2ALDH1A1NPSR1 | |
| SCHEMBL21113687 | 0.79 | KCNH2 (0.42) | KCNH2ALDH1A1NPSR1 | |
| SCHEMBL21113706 | 0.79 | KCNH2 (0.42) | KCNH2ALDH1A1NPSR1 | |
| SCHEMBL21113648 | 0.78 | FAAH (0.38) | KCNH2ALDH1A1MAPTNPSR1 | |
| SCHEMBL21113657 | 0.78 | KCNH2 (0.38) | KCNH2ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135697-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2019-08-14 | — | — | EP | claimed |