Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580070 | 0.83 | TACR1 (0.49) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL10475483 | 0.83 | CA1 (0.50) | TSHRPOLBCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL8817784 | 0.80 | TACR1 (0.49) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL18759588 | 0.75 | SLC6A4 (0.46) | TSHRIDO1HTR2AHTR2CSLC6A4 | |
| Cyclohexane SCHEMBL8149682 | 0.74 | TSHR (0.83) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL8116441 | 0.74 | CA1 (0.55) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL8116438 | 0.74 | CA1 (0.55) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL2702542 | 0.74 | IDO1 (0.46) | IDO1HTR2AHTR2CSLC6A4CYP3A4 | |
| SCHEMBL9662857 | 0.73 | CA1 (0.54) | TSHRPOLBCA1CA2CA7 | |
| SCHEMBL2701945 | 0.73 | CTSL (0.53) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135697-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2019-08-14 | — | — | EP | claimed |