SCHEMBL21239962

SCHEMBL21239962

CCOC(=O)CCC(=O)NC(Cc1ccc(-c2ccccc2)cc1)CC(C)C(=O)OCC

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 11/20 0.65
▸ ACE P12821 4/20 0.65
▸ MMEL1 Q495T6 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17746035 1.00 MME (0.65) MMEACEMMEL1
SCHEMBL25129465 0.95 MME (0.64) MMEACEMMEL1
SCHEMBL21727312 0.95 MME (0.64) MMEACEMMEL1
SCHEMBL28456484 0.94 MME (0.76) MMEACEMMEL1
SCHEMBL7436015 0.94 MME (0.76) MMEACEMMEL1
Sacubitril SCHEMBL22420467 0.92 MME (0.77) MMEACEMMEL1
Sacubitril SCHEMBL8214132 0.92 MME (0.77) MMEACEMMEL1
Sacubitril SCHEMBL1908525 0.92 MME (0.77) MMEACEMMEL1
Sacubitril SCHEMBL18059568 0.92 MME (0.77) MMEACEMMEL1
Sacubitril SCHEMBL2707112 0.92 MME (0.77) MMEACEMMEL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200038379-A1 PHARMACEUTICAL COMPOSITION WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2020-02-06 — — US claimed
CN-110237072-A The preparation method of pharmaceutical composition 武汉朗来科技发展有限公司 2019-09-17 — — CN claimed
EP-3524250-A1 PHARMACEUTICAL COMPOSITION Wuhan LL Science And Technology Development Co., Ltd. (CN) 2019-08-14 — — EP claimed
CN-109803657-B Pharmaceutical composition 武汉朗来科技发展有限公司 2022-07-29 — — CN disclosed
CN-110237072-B Process for preparing pharmaceutical composition 武汉朗来科技发展有限公司 2022-03-25 — — CN disclosed
CN-110237071-B Pharmaceutical preparation and use thereof 武汉朗来科技发展有限公司 2022-03-22 — — CN disclosed
US-20200038379-A1 PHARMACEUTICAL COMPOSITION WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2020-02-06 — — US disclosed
CN-110237072-A The preparation method of pharmaceutical composition 武汉朗来科技发展有限公司 2019-09-17 — — CN disclosed
EP-3524250-A1 PHARMACEUTICAL COMPOSITION Wuhan LL Science And Technology Development Co., Ltd. (CN) 2019-08-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200038379-A1 PHARMACEUTICAL COMPOSITION MME, ANPEP, TMPRSS15 MME 1/4885ACE 32/4885MMEL1 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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