Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 10/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 10/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607786 | 0.83 | TOP2A (0.47) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Sulfuric Acid SCHEMBL11349184 | 0.82 | TOP2A (0.51) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Benzene SCHEMBL28095234 | 0.82 | IKBKB (0.53) | CKS1BSKP2GLO1TOP2AIKBKB | |
| SCHEMBL28859500 | 0.82 | IKBKB (0.53) | CKS1BSKP2GLO1TOP2AIKBKB | |
| SCHEMBL28868 | 0.82 | IKBKB (0.53) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Bicarbonate SCHEMBL28398978 | 0.80 | TOP2A (0.56) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Hydrochloric Acid SCHEMBL17396321 | 0.80 | IKBKB (0.52) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Ammonia Solution, Strong SCHEMBL17396339 | 0.80 | IKBKB (0.52) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Hydrochloric Acid SCHEMBL21643628 | 0.80 | IKBKB (0.52) | CKS1BSKP2GLO1TOP2AIKBKB | |
| Hydrochloric Acid SCHEMBL5385347 | 0.80 | IKBKB (0.52) | CKS1BSKP2GLO1TOP2AIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994385-B1 | CHANGED CONDITION INDICATOR | COOPERMAN ISADORE (US) | 2019-08-14 | — | — | EP | disclosed |