Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509736 | 1.00 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28868 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Benzene SCHEMBL28095234 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL28859500 | 0.98 | IKBKB (0.53) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL8685286 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Ammonia Solution, Strong SCHEMBL17396339 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL1238416 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL5341478 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL17396321 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 | |
| SCHEMBL918377 | 0.96 | IKBKB (0.52) | IKBKBCHUKDAPK3JAK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11644423-B2 | Optochemical sensor unit and a method for the qualitative and/or quantitative determination of an analyte in a measuring medium with the sensor unit | ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) | 2023-05-09 | — | — | US | disclosed |
| US-20210055227-A1 | OPTOCHEMICAL SENSOR UNIT AND A METHOD FOR THE QUALITATIVE AND/OR QUANTITATIVE DETERMINATION OF AN ANALYTE IN A MEASURING MEDIUM WITH THE SENSOR UNIT | ENDRESS HAUSER CONDUCTA GMBH CO KG (DE) | 2021-02-25 | — | — | US | disclosed |
| US-10866192-B2 | Optochemical sensor unit and a method for the qualitative and/or quantitative determination of an analyte in a measuring medium with the sensor unit | ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) | 2020-12-15 | — | — | US | disclosed |
| US-20200124537-A1 | OPTOCHEMICAL SENSOR UNIT AND A METHOD FOR THE QUALITATIVE AND/OR QUANTITATIVE DETERMINATION OF AN ANALYTE IN A MEASURING MEDIUM WITH THE SENSOR UNIT | ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) | 2020-04-23 | — | — | US | disclosed |
| US-20200041412-A1 | SENSOR MEMBRANE, SENSOR CAP AND/OR OPTICAL SENSOR AND METHOD FOR MANUFACTURING A SENSOR MEMBRANE | ENDRESS+HAUSER CONDUCTA GMBH+CO. KG (DE) | 2020-02-06 | — | — | US | disclosed |