Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316807 | 0.91 | CDK2 (0.44) | CDK2CCNE2CCNE1AHRGBA1 | |
| SCHEMBL30579354 | 0.91 | AHR (0.43) | CDK2CCNE2CCNE1AHRIP6K1 | |
| SCHEMBL2356743 | 0.91 | AHR (0.43) | CDK2CCNE2CCNE1AHRIP6K1 | |
| SCHEMBL20981874 | 0.89 | CDK2 (0.45) | CDK2CCNE2CCNE1AHRGBA1 | |
| SCHEMBL2311943 | 0.86 | CDK2 (0.43) | CDK2CCNE2CCNE1AHRGBA1 | |
| SCHEMBL30315466 | 0.86 | CDK2 (0.43) | CDK2CCNE2CCNE1AHRGBA1 | |
| SCHEMBL2358698 | 0.86 | CCNE2 (0.56) | CDK2CCNE2CCNE1AHRIP6K1 | |
| SCHEMBL20541983 | 0.85 | NTRK1 (0.41) | CDK2CCNE2CCNE1AHRCDK5 | |
| SCHEMBL20557731 | 0.83 | CDK5 (0.41) | CDK2CCNE2CCNE1AHRCDK5 | |
| SCHEMBL2316607 | 0.83 | CDK2 (0.44) | CDK2CCNE2CCNE1AHRGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-A1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | Novartis AG (CH) | 2019-08-14 | — | — | EP | disclosed |