Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174186 | 0.79 | CHRNB2 (0.44) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11918316 | 0.79 | CHRNB2 (0.44) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14473817 | 0.77 | CHRNB2 (0.45) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14599861 | 0.76 | HCAR2 (0.47) | ATMHCAR2CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL12017395 | 0.75 | CHRNB2 (0.48) | ATMCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17614045 | 0.75 | CHRNB2 (0.44) | ATMCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL14473815 | 0.75 | CYP2D6 (0.46) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5834552 | 0.75 | SMN1; SMN2 (0.58) | L3MBTL1 | |
| SCHEMBL17921383 | 0.74 | NPC1 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL14474331 | 0.74 | CYP11B1 (0.45) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |