Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137984 | 0.91 | MAP4K4 (0.44) | MAP4K4CCR1CCR5CCR8HDAC6 | |
| SCHEMBL27583691 | 0.85 | HRH3 (0.42) | MAP4K4HRH4ALDH1A1TP53HRH3 | |
| SCHEMBL5687883 | 0.83 | KDM1A (0.44) | MAP4K4HRH4CCR1CCR5CCR8 | |
| SCHEMBL23183059 | 0.83 | PDGFRB (0.39) | CCR1CCR5CCR8HDAC6SSTR3 | |
| SCHEMBL22258920 | 0.81 | MAP4K4 (0.47) | MAP4K4HRH4PDE10AHRH3 | |
| SCHEMBL21600612 | 0.81 | PDE10A (0.37) | CCR1CCR5CCR8HDAC6NPC1 | |
| SCHEMBL10229782 | 0.79 | CYP1A2 (0.51) | HRH4HTR3ATRPA1NPC1RAB9A | |
| SCHEMBL24294949 | 0.79 | MAP4K4 (0.39) | MAP4K4CCR1CCR5CCR8HDAC6 | |
| SCHEMBL28819054 | 0.79 | NFE2L2 (0.44) | HRH4HTR3ATRPA1NPC1RAB9A | |
| SCHEMBL17888396 | 0.77 | MAP4K4 (0.52) | MAP4K4HRH4PDE10AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |