Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951314 | 0.81 | GAA (0.35) | CYP11B2GAACYP2C19PDE10ACHRM5 | |
| SCHEMBL9297200 | 0.70 | PDE10A (0.42) | GAACYP2C19PDE10ACHRM5KDM4E | |
| SCHEMBL11477085 | 0.69 | MAP4K4 (0.47) | GAACYP2C19PDE10AALDH1A1POLB | |
| SCHEMBL21233156 | 0.69 | CYP11B2 (0.43) | CYP11B2GAACYP2C19CREBBPBRD4 | |
| SCHEMBL21233338 | 0.69 | CYP11B2 (0.51) | CYP11B2GAACYP2C19CREBBPBRD4 | |
| SCHEMBL11469863 | 0.68 | MAP4K4 (0.54) | PDE10AKDM4EALDH1A1KDRMAPK1 | |
| SCHEMBL21233354 | 0.67 | CYP11B2 (0.42) | CYP11B2GAACYP2C19CREBBPBRD4 | |
| SCHEMBL23143459 | 0.67 | KDR (0.54) | PDE10AKDRRET | |
| SCHEMBL15639819 | 0.67 | PDE10A (0.41) | GAACYP2C19PDE10AKDM4EALDH1A1 | |
| SCHEMBL25418803 | 0.66 | CYP11B2 (0.53) | CYP11B2KITGAACREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |