Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.63 |
| ▸ | CCR5 | P51681 | 2/20 | 0.63 |
| ▸ | CCR8 | P51685 | 2/20 | 0.63 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181893 | 0.79 | CCR1 (1.00) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL29397106 | 0.79 | CCR1 (1.00) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL31482988 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL31482991 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL32670845 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| Hydrochloric Acid SCHEMBL9639295 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| Hydrochloric Acid SCHEMBL5549447 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL2258309 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL6820852 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL6820765 | 0.77 | CCR1 (0.94) | CCR1CCR5CCR8METAP2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |