Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422361 | 0.75 | CCR1 (0.75) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL13680695 | 0.74 | ADORA2A (0.55) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL13483700 | 0.73 | CCR1 (0.71) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL30625193 | 0.73 | CCR1 (0.52) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL12269967 | 0.73 | CCR1 (0.52) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL19539189 | 0.72 | KDM5A (0.41) | MAPK14ACHEMAOAPPARA | |
| SCHEMBL196966 | 0.72 | CCR1 (1.00) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL29388304 | 0.72 | CCR1 (1.00) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL30511194 | 0.72 | CCR1 (1.00) | CCR1CCR8CYP2A6TGFBR1MAPK14 | |
| SCHEMBL12605587 | 0.72 | KDM4E (0.48) | CCR1CCR8CYP2A6ACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |