Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907670 | 0.79 | KDM4E (0.43) | KDM4ETDP1ALOX12CYP3A4LMNA | |
| SCHEMBL28064354 | 0.79 | P2RX3 (0.38) | KDM4ETDP1ALOX12CYP3A4ALDH1A1 | |
| SCHEMBL907751 | 0.78 | TNFSF11 (0.41) | KDM4ETDP1ALOX12CYP3A4ALDH1A1 | |
| SCHEMBL27845042 | 0.75 | KDM4E (0.39) | KDM4ETDP1ALOX12CYP3A4LMNA | |
| SCHEMBL21854525 | 0.75 | CYP17A1 (0.40) | PTGS1PTGS2CYP17A1 | |
| SCHEMBL16742632 | 0.73 | HTT (0.38) | KDM4ETDP1ALOX12CYP3A4LMNA | |
| SCHEMBL24260568 | 0.73 | IRAK4 (0.34) | KDM4ETDP1ALOX12CYP3A4LMNA | |
| SCHEMBL10033203 | 0.73 | — | — | |
| SCHEMBL27638774 | 0.71 | KDM4E (0.40) | KDM4ETDP1ALOX12CYP3A4LMNA | |
| SCHEMBL20345741 | 0.71 | CYP17A1 (0.33) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |