Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.39 |
| ▸ | PDE2A | O00408 | 6/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330989 | 0.76 | PDE10A (0.42) | PDE10APDE2APDE5APDE11APDGFRB | |
| SCHEMBL21240997 | 0.75 | HSD17B10 (0.48) | GAAKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL21241500 | 0.74 | ADORA2A (0.45) | PDE10AGAAKDM4EHPGDMITF | |
| SCHEMBL21241506 | 0.72 | PDE10A (0.43) | PDE10APDE2APDE5APDE11AHPGD | |
| SCHEMBL21241175 | 0.69 | PDE4B (0.43) | PDE10ALMNAPDGFRBPDE4DMAPT | |
| SCHEMBL1264612 | 0.69 | KIT (0.60) | PDE10APDGFRBPDGFRA | |
| SCHEMBL4370352 | 0.68 | — | — | |
| SCHEMBL29413198 | 0.68 | — | — | |
| SCHEMBL29889827 | 0.67 | NOTUM (0.49) | PDE10AMAPT | |
| SCHEMBL2486570 | 0.67 | NOTUM (0.49) | PDE10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |