Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21240997 | 0.86 | HSD17B10 (0.48) | ADORA2AADORA1MAPTKDM4EALDH1A1 | |
| SCHEMBL22598458 | 0.82 | KIF11 (0.41) | KDM4ELMNA | |
| SCHEMBL21241506 | 0.82 | PDE10A (0.43) | MAPTKMT2ALMNAHTTHPGD | |
| SCHEMBL21241175 | 0.77 | PDE4B (0.43) | ADORA2AADORA1MAPTKMT2ALMNA | |
| SCHEMBL21241363 | 0.76 | ADORA2A (0.45) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL21241177 | 0.75 | S1PR1 (0.37) | PDE10A | |
| SCHEMBL21241358 | 0.74 | PDE10A (0.39) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL21241508 | 0.71 | PDE10A (0.35) | MAPTKDM4EKMT2AALDH1A1LMNA | |
| SCHEMBL21241365 | 0.70 | ADORA2A (0.43) | ADORA2AADORA1ALDH1A1LMNA | |
| SCHEMBL23664426 | 0.69 | PDE10A (0.35) | MAPTKDM4EKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |