Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998707 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL10912057 | 0.77 | MEN1 (0.67) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL813081 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL10912055 | 0.77 | MEN1 (0.67) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL28386265 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL24366969 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL7475872 | 0.76 | SLC1A3 (0.60) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL7462670 | 0.76 | SLC1A3 (0.60) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL18697078 | 0.76 | SLC1A3 (0.60) | ALDH1A1KMT2AMEN1HTTCA1 | |
| SCHEMBL7457180 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149738-A1 | PROTEIN KINASE MKK4 INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH | HEPAREGENIX GMBH (DE) | 2019-08-08 | — | — | WO | disclosed |