Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.59 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16157013 | 0.83 | PDE3B (0.66) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL22909978 | 0.83 | PDE3B (0.59) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL9655922 | 0.83 | PDE3B (0.59) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL11487972 | 0.80 | PDE3B (0.56) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL10558594 | 0.80 | PDE3B (0.65) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL21970685 | 0.80 | PDE3B (0.65) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL10353457 | 0.80 | PDE3B (0.71) | PDE3BPDE3ATNNC1PDE4APDE4B | |
| SCHEMBL11368140 | 0.80 | PDE3B (0.58) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL9654449 | 0.79 | PDE3B (0.60) | PDE3BPDE3ATNNC1KDM4EALDH1A1 | |
| SCHEMBL7293274 | 0.78 | PDE3B (0.59) | PDE3BPDE3ATNNC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149259-A1 | P2Y12 RECEPTOR ANTAGONIST CONTAINING GUANIDYL, AND PREPARATION METHOD AND USE THEREOF | 安徽省新星药物开发有限责任公司 | 2019-08-08 | — | — | WO | disclosed |