Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544610 | 0.79 | CCNC (0.49) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL23674615 | 0.79 | HTT (0.42) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL7857287 | 0.78 | HTT (0.36) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL18858537 | 0.77 | AOC1 (0.43) | GSK3BPTGDR2AOC1AOC3GABRA1 | |
| SCHEMBL7213436 | 0.76 | CYP2E1 (0.47) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL7662114 | 0.76 | HTT (0.42) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL3074174 | 0.76 | HTT (0.42) | HTTKMT2AMEN1SLC22A12CCNC | |
| SCHEMBL4544573 | 0.75 | CYP11B1 (0.39) | HTTKMT2AMEN1CCNCCDK8 | |
| SCHEMBL30100719 | 0.75 | SLC6A4 (0.42) | HTTKMT2AMEN1CCNCCDK8 | |
| SCHEMBL23517169 | 0.75 | KMT2A (0.41) | HTTKMT2AMEN1SLC22A12CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |